I've been slowly processing the open-window aerial photography tour photos of the Purcell Mountains. These were hand-held on a Nikon D800E (no stabilization), shot at ISO 1600 (moderate noise), 1/2000 second shutter speed. Almost all of them are quite sharp. 1/2000 seems to be my workhorse shutter speed for handheld aerials. Most were underexposed by 1-2 stops, which was fixed in post-processing. These settings were a trade-off between sharpness (shutter speed), noise (ISO), and exposure. I preferred to underexpose while getting a sharp photo with manageable noise.
I used DxO Optics Pro's Prime Noise reduction algorithm, which is head and shoulders above all the other noise reduction algorithms I've used. Settings (in the Advanced Menu) were Luminance = 0, Chrominance = 10 or 20 (10% or 20% of of maximum).
Here are some of the latest processed photos. Great flight. See more in our Purcell Mountains - British Columbia Gallery.